ImaGene® 9.0

Category Genomics>Gene Expression Analysis/Profiling/Tools

Abstract ImaGene® 9.0 from BioDiscovery is a leading-edge microarray analysis software product that offers optimal performance with some of the broadest and most refined features available today.

Through proprietary machine vision technology, ImaGene 9.0 delivers high quality data and advanced automation to quantify, normalize and analyze your microarray experiments.

ImaGene 9.0 and the manufacturer's complementary modules for expression analysis (Nexus Expression™) and aCGH analysis (ImaGene CGH) enable the broadest and most refined microarray data analysis.

ImaGene 9.0 offers advanced features allowing you to rapidly explore the data from your microarray experiments with the highest level of confidence in its integrity.

Products features/capabilities include:

Most Advanced Automation --

1) Spot Finding & Grid Placement - patented and efficient algorithms automatically thread a grid through each data point, performing thousands of calculations per second ensuring optimal placement and alignment.

2) Spot & Array-Level Quality Control - ImaGene 9.0 will automatically analyze every spot and the array itself to determine the quality of the array image or individual spots, minimizing the need for laborious manual inspection of tens of thousands of spots, allowing users to have confidence in the reported measurements.

Highest Quantification Accuracy --

1) Patented Automated Segmentation - proprietary algorithms and processes are used to automate a precise segmentation process, discriminating between signal, background and contamination, ensuring the highest quality experimental data.

This unique feature can even salvage contaminated spots by automatically removing artifacts that statistically do Not match the signal or background intensity profiles.

One-Button Batch Processing --

1) The optional batch-processing module enables rapid, completely hands-free processing of any number of images. This feature brings new efficiency to high-throughput environments where large numbers of arrays are processed each day.

And, to keep check on workflow, an intuitive progress window shows you where you are along the way.

Elegant Interface and Navigation --

1) Easy to learn and use - ImaGene 9.0 continues a tradition of an intuitive design that is easy to learn to use and is similarly easy to navigate. With tabular formats and sliders, creating and managing settings is as simple as a click of a mouse.

2) Interactive and integrated - with interactive and integrated tabular and graphical data views, ImaGene lets you see the correlations between images and related data with a wide variety of interactive plots (histogram, box, scatter, GenePie and M-A plots).

Analysis Modules --

1) Flexible options in ImaGene 9.0 can provide: multiple data normalization options including lowess on entire array; sub-grid or control spots; differential regulation analysis and visualization using Nexus Expression-Lite; and statistical aCGH analysis and visualization using Nexus Solo.

System Compatibility --

1) ImaGene 9.0 is platform independent as it is available for Windows, MAC and Linux operating systems; is compatible with a broad variety of microarray types [staggered/orange packing, protein, array comparative genomic hybridization (aCGH), etc.] from a large number of manufacturers as well as home spotted arrays.

Additional Features --

1) Highly flexible in providing automated features requiring limited user interaction and manual features for asserting more user control when needed.

2) Scanner independent – works with all scanners including Tecan, Agilent, GenePix (Axon), Perkin Elmer, Innopysis, and more.

3) Ready to use templates for many commercial arrays including Agilent 244K, 4x44K, 44K arrays and Exiqon's miRCURY LNA™ microRNA Arrays.

NEW in ImaGene 9.0 -- The new and improved features in ImaGene 9.0 offer substantial performance improvement and higher quality allowing you to get to the results even faster.

1) Improved memory for efficient loading and processing of the latest high density arrays (e.g. 1M probes).

2) A consolidated and streamlined new grid format containing both grid structure and GeneID information.

3) A new design focused on core image quantification and visualization removing downstream analysis tools.

4) Ability to add optional modules for further analysis of gene/miRNA expression (Nexus Expression™-Lite) and CGH analysis (Nexus Solo™).

Additional Data Analysis features --

1) Integrated data visualization tools in the core ImaGene application for quality, trend and regulation assessment.

2) M-A, histogram, box, scatter and GenePie Plots.

Optional --

1) aCGH analysis and visualization module - (ImaGene CGH) - (See G6G Abstract Number 20129R).

2) Gene regulation analysis and visualization module - (Nexus Expression™) - (See G6G Abstract Number 20006A).

3) One-Button batch automation module.

System Requirements

Manufacturer

Manufacturer Web Site ImaGene

Price Contact manufacturer.

G6G Abstract Number 20128R

G6G Manufacturer Number 100431