MolQuest version 2.0.3

Category Cross-Omics>Sequence Analysis/Tools and Genomics>Gene Expression Analysis/Profiling/Tools

Abstract MolQuest is one of the most comprehensive, easy-to-use desktop applications for sequence analysis and molecular biology data management. MolQuest version 2.0.3 is now released and available for download as a trial version.

It includes one of the fastest and most accurate families of eukaryotic gene finding programs, fgenesh/fgenesh+, for a variety of different genomes, as well as pipelines for fully automatic annotation of eukaryotic (fgenesh++) and bacterial (fgenesb) genomes, that were widely used in scientific publications and are well known for their accuracy.

MolQuest provides a user-friendly interface for primer design, internet database searches, gene prediction, promoter identification, regulatory elements mapping, patterns discovery protein analysis, multiple sequence alignment, phylogenetic reconstruction, and a wide variety of other functions, for instance:

1) Run common bioinformatics tasks, such as Basic Local Alignment Search Tool (BLAST) search and gene finding, on batches of sequences.

2) Customize data analysis using sophisticated and configurable options.

3) Annotate and visualize results, facilitating interpretation and presentation of data.

4) Representation of a project, as a schematic block for convenient creation of pipeline links.

5) The possibility to process several projects simultaneously.

6) Allows the user to integrate any console application(s) into the MolQuest GUI shell.

MolQuest, with its friendly interface, is particularly suited for education and learning bioinformatics, university students, MSc or PhD research projects, as well as for integration of bioinformatics into high school and college curriculums.

Note: MolQuest contains more than 130 programs and 9 viewers for analysis of biomedical data.

Products main features/capabilities include:

1) Gene Finding: Gene models construction; splice sites, protein-coding exons.

2) Bacterial Promoter, Operon and Gene Finding.

3) Gene finding using similarity with expressed sequence tags (ESTs), Protein or other genome sequences.

4) Gene Finding -- in Viral Genomes.

5) Sequence Comparison -- Sequences alignment, Alignment with genome, Alignment genomes.

6) Sequence Comparison -- Multiple alignments for protein sequences and multiple alignments for nucleotide sequences.

7) Protein Analysis -- Protein Location and Prosite (a database of protein families and domains) Pattern finding.

8) Protein Analysis -- Protein secondary structure.

9) Protein Analysis -- Protein/DNA 3D-Visual Works.

10) Genome Visualization Tools -- Genome Explorer / Infogene database (of Known genes of many organisms).

11) Analysis of gene expression data -- (SelTag) -- SelTag is one of the best-of-breed tools for analyzing gene expression data.

It allows you to:

12) Search for motifs -- Search for promoters/functional motifs.

13) Find and Map repeats -- Find and map repeats in small genomes.

14) Sequences manipulation -- Manipulations with sequences.

15) Sequences manipulation -- RNA structures.

16) Clustering ESTs and Synteny -- Clusters of ESTs.

17) Clustering ESTs and Synteny (The condition of two (2) or more genes being located on the same chromosome whether or Not there is demonstrable linkage between them.) -- Human Synteny - Mouse Synteny - Rat Synteny.

System Requirements

See Downloads page.

Note: Some programs use statistical functions from the R free software environment for statistical computing and graphics and require the R-package to be installed on your computer.

Manufacturer

Manufacturer Web Site MolQuest version 2.0.3

Price Contact manufacturer.

G6G Abstract Number 20126R

G6G Manufacturer Number 102410